• Is large, encapsulated bean shaped organ with the spongy interior which located on the left side of the body below diaphragm.
  • It is one of the leading organs on maintaining immune reactions to antigens in the blood stream.
  • Blood-borne antigens and lymphocytes are transfered to the spleen via the splenic artery.
  • The splenic red pulp composed of a network of sinusoids inhabited by macrophages and various red blood cells (erythrocytes) and lymphocytes; it is the place where old and defective red blood cells are destroyed and removed.
  • The splenic white pulp surrounds the branches of the splenic artery, forming a periarteriolar lymphoid sheath (PALS) colonized mostly by T lymphocytes.

Source: Answer in Genesis, by Dr. David Menton.

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